منابع مشابه
Endocrine taste cells.
In taste cells, taste receptors, their coupled G proteins and downstream signalling elements mediate the detection and transduction of sweet, bitter and umami compounds. In some intestinal endocrine cells, taste receptors and gustducin contribute to the release of glucagon-like peptide 1 (GLP-1) and other gut hormones in response to glucose and non-energetic sweeteners. Conversely, taste cells ...
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It is known that a subset of taste cells generate action potentials in response to taste stimuli. However, responsiveness of these cells to particular tastants remains unknown. In the present study, by using a newly developed extracellular recording technique, we recorded action potentials from the basolateral membrane of single receptor cells in response to taste stimuli applied apically to ta...
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While the taste periphery has been studied for over a century, we are only beginning to understand how this important sensory system is maintained throughout adult life. With the advent of molecular genetics in rodent models, and the upswing in translational approaches that impact human patients, we expect the field will make significant advances in the near future.
متن کاملSingle Lgr5- or Lgr6-expressing taste stem/progenitor cells generate taste bud cells ex vivo.
Leucine-rich repeat-containing G protein-coupled receptor 5 (Lgr5) and its homologs (e.g., Lgr6) mark adult stem cells in multiple tissues. Recently, we and others have shown that Lgr5 marks adult taste stem/progenitor cells in posterior tongue. However, the regenerative potential of Lgr5-expressing (Lgr5(+)) cells and the identity of adult taste stem/progenitor cells that regenerate taste tiss...
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Evidence are now given that immune cells expressed endocrine markers like neuropeptides, biogenic amine, neuropeptide processing enzymes, regulated secretion pathway. In clear, immune cells expressed like the nervous system an endocrine phenotype. This give the following question: what can we now consider as immune or endocrine?
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ژورنال
عنوان ژورنال: British Journal of Nutrition
سال: 2014
ISSN: 0007-1145,1475-2662
DOI: 10.1017/s0007114513002262